Background Most common gynaecological carcinoma in developed countries Japan and Asia have 5 times lower incidence Most cases are post-menop...

Neoplasia
Neoplasia literally means "new growth.“ Sir Willis’s definition of Neoplasia : "an abnormal mass of tissue the growth of which e...

Essential Alterations for Malignant Transformation
Self sufficiency in growth and cell division Protooncogenes - genes in normal cells which encode proteins that have normal function in cells...

Carcinogenesis and Paraneoplastic Syndrome
Some occupational cancers Arsenic: lung, skin, hemangiosarcoma Asbestos: lung, mesothelioma, esophagus, stomach Benzene: leukemia, lymphoma ...

Relative frequency of different breast carcinoma.
In Situ Carcinoma 15–30 Ductal carcinoma in situ 80 Lobular carcinoma in situ 20 Invasive Carcinoma 70–85 No special type carcinoma ("d...

Invasive Carcinomas of Breast.
Ductal (No special type) Lobular Tubular/cribriform Mucinous Medullary Papillary metaplastic Invasive ductal carcinoma : is a term used for ...

Ductal Carcinoma in Situ.
DCIS tends to fill, distort, and unfold involved lobules and thus appears to involve ductlike spaces. In contrast, LCIS usually expands but ...

Lobular Carcinoma in Situ.
The cells are monomorphic with bland, round nuclei and occur in loosely cohesive clusters in ducts and lobules. Intracellular mucin vacuoles...